KACI: A Cancer Registry Platform Replacing Legacy Systems

Cancer registry software has historically been driven by legacy platforms that, while reliable, were not engineered for the scale, interoperability, and intelligence required by today’s Oncology Data Specialists (ODSs), multi-facility reporting, and evolving standard-setter requirements. Modern oncology data management demands more than manual abstraction, siloed interfaces, and cumbersome updates—it requires real-time intelligence, automated workflows, and a cloud-native foundation.

That’s where NeuralFrame’s KACI (Knowledge Assistant for Clinical Information) comes in. Built from the ground up with a FHIR-native architecture and AI-powered clinical abstraction, KACI streamlines registry operations, accelerates case completion, and dramatically reduces the workflow inefficiencies that plague legacy systems.

What Makes KACI Different?

At its core, KACI is more than a registry system—it’s a modern oncology data intelligence platform that automates casefinding, guides abstraction, simplifies reporting, and supports multi-facility visibility, all while keeping pace with rapidly changing reporting standards.

Key capabilities include:

  • AI-Assisted Abstraction & Real-Time Edits: KACI’s intuitive interface identifies and highlights edit requirements instantly, linking every field to relevant standard-setter guidelines (CoC, SEER, NAACCR) for faster, more accurate abstraction.

  • Automatic Updates & Standard-Setter Alignment: NeuralFrame monitors accrediting bodies and integrates changes within days, ensuring your registry is always up-to-date without manual patching.

  • FHIR-Native Interoperability: Built on modern HL7 FHIR, KACI connects to EMRs in real time—reducing bottlenecks and ensuring clean, structured data across clinical sources.

  • Cloud-Native SaaS Platform: Zero on-premises servers, automated updates, built-in SSO/Active Directory support, and high-grade security (SOC 2 Type II + HIPAA) make the system fast, secure, and reliable.

  • Scalable Multi-Facility Reporting and Dashboards: Whether tracking a single hospital or an integrated health system, KACI provides holistic insights and easy data rollups.

KACI vs. Legacy Cancer Registry Systems

Here’s a snapshot of how KACI stacks up against common legacy platforms, like Q-Centrix, CNExt, or Metriq:

Feature / Capability KACI (NeuralFrame) Legacy Cancer Registry Systems
Cloud-Native SaaS ✔️ Automatic updates, no on-prem servers or maintenance ❌ Often on-premise or lightly hosted with ongoing IT overhead
AI-Assisted Abstraction ✔️ Real-time edit guidance and NLP-powered insights ❌ Primarily manual abstraction with limited automation
FHIR-Native Interoperability ✔️ Full FHIR support for modern EMR connectivity ❌ Relies on legacy HL7, flat files, or custom interfaces
Standard-Setter Update Velocity ✔️ Updates delivered within days of publication ❌ Updates often take weeks or months
Multi-Facility Reporting ✔️ Unified dashboards with system-wide visibility and drill-downs ❌ Fragmented views and complex consolidation
Security & Compliance ✔️ SOC 2 Type II and HIPAA-compliant cloud architecture ❌ Security posture varies by vendor and deployment
Ease of Transition ✔️ Streamlined data migration completed in days or weeks ❌ Lengthy, manual conversions with higher risk

Why Registry Teams Are Choosing KACI

Cancer registrars and data teams increasingly report that legacy systems—built long before standardized API-driven interoperability and clinical AI—have become costly and slow to adapt. KACI solves these challenges by delivering:

💡 Significant Productivity Gains

By pre-populating fields and automating casefinding from pathology and EMR data, KACI reduces manual work and transcription errors, letting your team spend time on analysis, not data entry.

📊 Better Data Quality and Compliance

With up-to-date standard-setter integration and built-in validation, your abstracts and accreditation reports are not just accurate—they’re audit-ready.

🚀 Scalability for Growth

Whether you’re expanding services or consolidating systems across facilities, KACI scales with your registry’s needs without costly hardware upgrades.

🔐 Security You Can Trust

NeuralFrame’s rigorous security audits and compliance seals give IT teams confidence in protection—especially important for remote and hybrid ODS workflows.

Future-Ready Registry Software Starts with KACI

The oncology data landscape is evolving rapidly. Legacy systems simply can’t keep pace with modern interoperability standards, real-time clinical abstraction, or the scalability requirements of today’s cancer programs.

KACI isn’t just the next generation of cancer registry software—it’s the platform every forward-thinking registry team needs to improve accuracy, reduce workload, and unlock deeper insight from clinical data.

Ready to see how KACI compares to your current system? Schedule a demo today.